Datacenter or desktop?
For datacenter, my employer owns the DC and just worries about physical and access security. No one gets into the DC who isn't a pretty small subset of employees/contractors. We don't lock down BIOS but there is a lot of encryption on our systems because of contractual agreements (i.e., our customers who insist on encrypted data in transit/data at rest, regulatory stuff about PII, etc.) It'd be a pretty extraordinary event for someone to get into the DC, unrack a server (or a SAN
and take it away. A bigger risk is a disgruntled employee who brings a portable hard drive to work (or runs some sort of destructive program).
For stuff we have in public DCs, we tend to encrypt but not BIOS lock. If someone steals the hardware (again, a pretty extraordinary event even though we're trusting someone else's physical security), they can get around any BIOS lock anyway...we're only interested that they don't get the data. And of course, encrypt network.
For desktop, we encrypt laptops and do the basic stuff for mobile but that's it. Our cloud exposure is greater - a lot of our stuff is off in cloud land (AWS, Office 365, Azure, etc.) so that's by definition accessible from anywhere. No theft needed.
A friend works for the IRS. They do the whole bit at the desktop - BIOS is locked down with administrator password, chassis intrusion, any insert of USB sends an alert to IT, very locked down in terms of rights, etc.