...but people trust companies like Dropbox, Microsoft, Google, etc? :lol:
It's kind of a tradeoff. Yes, with big companies you get some peace of mind that supposedly they're big, professional, audited, etc. On the other hand, with anonymous encrypted storage you don't have to worry about government snoops or companies rifling through your data. I don't think stuff you store on Dropbox or OneDrive is even encrypted (unless you do it). Snowden remarked that looking at people's private pictures, etc. was something of a organizational past-time/fringe benefit...I very much doubt that private sector employees are any less nosy/curious.
I think the phrase "regardless of encryption" is strange. Right now I have a PasswordSafe database sitting on Dropbox. Inside are my logins for dozens of sites/servers, plus credit card info, etc. If someone were to break into Dropbox, I wouldn't lose any sleep. I'd be comfortable putting a plain-text copy of it on tarsnap, because I know the crypto involved and it's very good (and if I have doubts, I can read the source code).
Encryption means encryption.
I think there are technical challenges to this sort of thing, but probably no more so than other file-sync/file-storage services.